The impact of variation in the number of CD8(+) T-cell precursors on the outcome of virus infection.
We investigated the role of varying the initial number of naive antiviral CTL precursors on the dynamics of LCMV-DOCILE infection. C57BL/6 mice, exhibiting LCMV-specific CTLp frequencies of about 50, are protected against virus persistence over a range of infectious doses up to 10(4) pfu. With 10-fo...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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