IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis.
BACKGROUND: IL-1beta has the potential to promote progressive renal disease by effects on macrophage recruitment and activation or by effects mediated through tubular cell transforming growth factor (TGF)-beta production, previously demonstrated in vitro. METHODS: The in vivo roles of endogenous IL...
主要な著者: | , , , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2009
|