Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Determining the genetic bases of age-related disease remains a major challenge requiring a spectrum of approaches from human and clinical genetics to the utilization of model organism studies. Here we report a large-scale genetic screen in mice employing a phenotype-driven discovery platform to iden...

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Հիմնական հեղինակներ: Potter, PK, Bowl, MR, Jeyarajan, P, Wisby, L, Blease, A, Goldsworthy, ME, Simon, MM, Greenaway, S, Michel, V, Barnard, A, Aguilar, C, Agnew, T, Banks, G, Blake, A, Chessum, L, Dorning, J, Falcone, S, Goosey, L, Harris, S, Haynes, A, Heise, I, Hillier, R, Hough, T, Hoslin, A, Hutchison, M, King, R, Kumar, S, Lad, HV, Law, G, MacLaren, RE, Morse, S, Nicol, T, Parker, A, Pickford, K, Sethi, S, Starbuck, B, Stelma, F, Cheeseman, M, Cross, SH, Foster, RG, Jackson, IJ, Peirson, SN, Thakker, RV, Vincent, T, Scudamore, C, Wells, S, El-Amraoui, A, Petit, C, Acevedo-Arozena, A, Nolan, PM, Cox, R, Mallon, AM, Brown, SD
Ձևաչափ: Journal article
Լեզու:English
Հրապարակվել է: Springer Nature 2016

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