The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.

BACKGROUND: Urokinase-type plasminogen activator (u-PA) promotes fibrinolysis by catalyzing the conversion of plasminogen to the active protease plasmin via the cleavage of a peptide bond. When localized to the external cell surface it contributes to tissue remodelling and cellular migration; inhibi...

詳細記述

書誌詳細
主要な著者: Spraggon, G, Phillips, C, Nowak, UK, Ponting, C, Saunders, D, Dobson, C, Stuart, D, Jones, E
フォーマット: Journal article
言語:English
出版事項: 1995