The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator.

BACKGROUND: Urokinase-type plasminogen activator (u-PA) promotes fibrinolysis by catalyzing the conversion of plasminogen to the active protease plasmin via the cleavage of a peptide bond. When localized to the external cell surface it contributes to tissue remodelling and cellular migration; inhibi...

書目詳細資料
Main Authors:	Spraggon, G, Phillips, C, Nowak, UK, Ponting, C, Saunders, D, Dobson, C, Stuart, D, Jones, E
格式:	Journal article
語言:	English
出版:	1995

相似書籍

Immunohistochemical localization of urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor and α2-antiplasmin in human corneal perforation: a case report
由: Sugioka Koji, et al.
出版: (2012-11-01)

TISSUE PLASMINOGEN-ACTIVATOR VERSUS UROKINASE
由: Ebers, G
出版: (1988)

Neuroprotection by urokinase plasminogen activator in the hippocampus
由: Eunsil Cho, et al.
出版: (2012-04-01)

Evaluation of Urokinase Plasminogen Activator Receptor, Soluble Urokinase Plasminogen Activator Receptor, and β1 Integrin in Patients with Hodgkin′s Lymphoma
由: Shirin Kouhpayeh, et al.
出版: (2017-01-01)

Urokinase-type Plasminogen Activator and Plasminogen Activator Inhibitor Induction by Etoposide in a Glioblastoma Cell Strain
由: Branko Brdar, et al.
出版: (2002-01-01)

Urokinase-type plasminogen activator blockade ameliorates experimental colitis in mice
由: Yoshifumi Kida, et al.
出版: (2023-02-01)

Urokinase-type plasminogen activator: a new target for male contraception?
由: Ying Qin, et al.
出版: (2015-04-01)

Urokinase-type plasminogen activator promotes synaptic repair in the ischemic brain
由: Ariel Diaz, et al.
出版: (2018-01-01)

Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator
由: Tobias Kromann-Hansen, et al.
出版: (2017-06-01)

Exogenous Urokinase Inhibits Proteasomal Degradation of Its Cognate Urokinase Plasminogen Activator Receptor
由: Ran Zhu, et al.
出版: (2022-08-01)

Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation
由: Kamlesh K. Gupta, et al.
出版: (2017-03-01)

Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration.
由: Kapustin, A, et al.
出版: (2012)

Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19
由: Tetiana Yatsenko, et al.
出版: (2024-01-01)

Serum levels of urokinase-type plasminogen activator in healthy dogs and oncologic canine patients
由: Sofia C. Ramos, et al.
出版: (2017-08-01)

Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
由: Lim Kyu, et al.
出版: (2006-08-01)

Urokinase-Type Plasminogen Activator System in Norm and in Life-Threatening Processes (Review)
由: Elena V. Kugaevskaya, et al.
出版: (2018-12-01)

Circulating Soluble Urokinase-Type Plasminogen Activator Receptor in Obstructive Sleep Apnoea
由: Renata Marietta Bocskei, et al.
出版: (2020-02-01)

Corrigendum: Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19
由: Tetiana Yatsenko, et al.
出版: (2024-03-01)

Ligand binding modulates the structural dynamics and activity of urokinase-type plasminogen activator: A possible mechanism of plasminogen activation.
由: Tobias Kromann-Hansen, et al.
出版: (2018-01-01)

Involvement of Urokinase-Type Plasminogen Activator Receptor in the Formation of a Profibrotic Microenvironment in the Epicardial Region
由: K. V. Dergilev, et al.
出版: (2021-12-01)

Increased expression of urokinase plasminogen activator and its cognate receptor in human seminomas
由: Sorrenti Salvatore, et al.
出版: (2010-04-01)

Inhibitors of Urokinase Type Plasminogen Activator and Cytostatic Activity from Crude Plants Extracts
由: Augusto Carvajal, et al.
出版: (2013-07-01)

Detection of soluble urokinase type plasminogen activator receptors in children with gingivitis and normal subjects
由: Mohamed Abd‑Ellatif El‑Patal, et al.
出版: (2022-10-01)

Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor
由: Bezerra Jorge A, et al.
出版: (2006-11-01)

Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer
由: Bing-Tao Zhai, et al.
出版: (2022-03-01)

Association between serum soluble urokinase-type plasminogen activator receptor and atrial fibrillation
由: Noboru Ichihara, et al.
出版: (2017-10-01)

Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness
由: Doljak Bojan, et al.
出版: (2009-10-01)

Soluble urokinase plasminogen activator receptor for the prediction of ventilator-associated pneumonia
由: Pouline M. van Oort, et al.
出版: (2019-03-01)

Crystallization and X-ray diffraction study of recombinant platelet-derived endothelial cell growth factor.
由: Spraggon, G, et al.
出版: (1993)

QSAR modelling to predict structural features of certain sulfonamide as Urokinase-type Plasminogen Activator inhibitors
由: Rahul D. Jawarkar, et al.
出版: (2024-06-01)

Serum soluble urokinase plasminogen activator receptor in adolescents: interaction of chronic pain and obesity
由: Hershel Raff, et al.
出版: (2020-08-01)

Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID‐19
由: Shengyuan Luo, et al.
出版: (2022-09-01)

<i>N</i>-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer
由: Lisa Belfiore, et al.
出版: (2020-07-01)

Soluble urokinase plasminogen activator receptor predicts mortality in exacerbated COPD
由: Nina S. Godtfredsen, et al.
出版: (2018-05-01)

Specific inhibitors of urokinase plasminogen activator for treatment of cancers; In silico approach
由: Benjamin Talbot, et al.
出版: (2020-05-01)

Kinetics of the soluble urokinase plasminogen activator receptor (suPAR) in cirrhosis.
由: Emilie Garnæs, et al.
出版: (2019-01-01)

Serum Soluble Urokinase Plasminogen Activator Receptor Levels in Resistant Hypertension
由: Nergiz Bayrakcı, et al.
出版: (2024-04-01)

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer
由: Auxtine Micalet, et al.
出版: (2023-12-01)

Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations.
由: Yue Shen, et al.
出版: (2012-01-01)

Soluble urokinase-type plasminogen activator receptor as a biomarker of treatment response in childhood tuberculosis
由: Ery Olivianto, et al.
出版: (2019-01-01)