Emerging evidence for cAMP-Ca2+ cross talk in heart atrial nanodomains where IP3-evoked Ca2+ release stimulates adenylyl cyclases

Calcium handling is vital to normal physiological function in the heart. Human atrial arrhythmias, eg. atrial fibrillation, are a major morbidity and mortality burden, yet major gaps remain in our understanding of how calcium signaling pathways function and interact. Inositol trisphosphate (IP3) is...

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Bibliographic Details
Main Authors: Burton, RB, Terrar, D
Format: Journal article
Language:English
Published: SAGE Publications 2021