Characterisation and development of aspirin inducible biosensors in E. coli and SimCells

A simple aspirin-inducible system has been developed and characterised in E. coli by employing the Psal promoter and SalR regulation system originally from Acinetobacter baylyi ADP1. Mutagenesis at the DNA binding domain (DBD) and chemical recognition domain (CRD) of the SalR protein in A. baylyi AD...

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Bibliographic Details
Main Authors: Chen, J, Steel, H, Wu, Y, Wang, Y, Xu, J, Rampley, C, Thompson, I, Papachristodoulou, A, Huang, W
Format: Journal article
Published: American Society for Microbiology 2019