Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study.

BACKGROUND: Glutamate carboxypeptidase II (GCPII) encodes for intestinal folate hydrolase and brain N-acetylated alpha-linked acidic dipeptidase. Previous studies provided conflicting results on the effect of the GCPII 1561C-->T polymorphism on folate and total homocysteine (tHcy) concentrat...

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Bibliographic Details
Main Authors: Halsted, C, Wong, D, Peerson, J, Warden, C, Refsum, H, Smith, A, Nygård, O, Ueland, P, Vollset, SE, Tell, G
Format: Journal article
Language:English
Published: 2007