Degraded collagenase deteriorates islet viability.

OBJECTIVE: The utilization of purified enzyme blends consisting of collagenase class I (CI) and II (CII) and neutral protease is an essential step for clinical islet isolation. Previous studies suggested that the use of enzyme lots containing degraded CI reduced islet release from human pancreata....

Полное описание

Библиографические подробности
Главные авторы: Brandhorst, H, Raemsch-Guenther, N, Raemsch, C, Friedrich, O, Kurfuerst, M, Korsgren, O, Brandhorst, D
Формат: Journal article
Язык:English
Опубликовано: 2008