Second generation catalytic enantioselective nucleophilic desymmetrization at P(V): improved generality, efficiency and modularity

A broadly improved second generation catalytic two-phase strategy for the enantioselective synthesis of chiral at phosphorus (V) compounds is described. This protocol, consisting of a bifunctional iminophosphorane (BIMP) catalyzed nucleophilic desymmetrization of prochiral, bench stable P(V) precurs...

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Bibliographic Details
Main Authors: Formica, M, Ferko, B, Marsh, T, Davidson, TA, Yamazaki, K, Dixon, DJ
Format: Journal article
Language:English
Published: Wiley 2024