Hydrogen bonding control in the oxidative cyclisation of 1,5-dienes

The regioselective dihydroxylation of a series of functionalised polyenes is described. Under acidic conditions, the osmate ester derivatives obtained from oxidation with OsO4/TMEDA undergo an intramolecular cyclisation reaction forming functionalised tetrahydrofurans with high stereoselectivity and...

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Bibliographic Details
Main Authors: Donohoe, T, Winter, J, Helliwell, M, Stemp, G
Format: Journal article
Language:English
Published: 2001