Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation.

Cytomegalovirus (CMV) infection is endemic in Gambian infants, with 62% infected by 3 months and 85% by 12 months of age. We studied the CD8 T-cell responses of infants to CMV following primary infection. CMV-specific CD8 T cells, identified with tetramers, showed a fully differentiated phenotype (C...

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Bibliographic Details
Main Authors: Miles, D, van der Sande, M, Jeffries, D, Kaye, S, Ismaili, J, Ojuola, O, Sanneh, M, Touray, E, Waight, P, Rowland-Jones, S, Whittle, H, Marchant, A
Format: Journal article
Language:English
Published: 2007