HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control.

The genetic polymorphism that has the greatest impact on immune control of human immunodeficiency virus (HIV) infection is expression of HLA-B*57. Understanding of the mechanism for this strong effect remains incomplete. HLA-B*57 alleles and the closely related HLA-B*5801 are often grouped together...

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Bibliographic Details
Main Authors: Kloverpris, H, Stryhn, A, Harndahl, M, van der Stok, M, Payne, R, Matthews, P, Chen, F, Riddell, L, Walker, B, Ndung'u, T, Buus, S, Goulder, P
Format: Journal article
Language:English
Published: 2012