The distribution of IgG subclasses in the lupus band suggests disease-specific alteration in subclass switching rather than polyclonal B-cell activation.

The distribution of IgG subclasses in the lupus band suggests disease-specific alteration in subclass switching rather than polyclonal B-cell activation.

Deposition of immunoglobulins in the skin of patients with lupus erythematosus (LE), demonstrable as a linear band 'lupus band' at the basement membrane zone (BMZ) by direct immunofluorescence, was first described in 1963. Four decades after the discovery of the lupus band, a basic questio...

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Autors principals:	Alahlafi, A, Wordsworth, P, Wojnarowska, F
Format:	Journal article
Idioma:	English
Publicat:	2004

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