The chemical biology of human metallo-β-lactamase fold proteins.
The αββα metallo β-lactamase (MBL) fold (MBLf) was first observed in bacterial enzymes that catalyze the hydrolysis of almost all β-lactam antibiotics, but is now known to be widely distributed. The MBL core protein fold is present in human enzymes with diverse biological roles, including cell detox...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2016
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