The chemical biology of human metallo-β-lactamase fold proteins.

The αββα metallo β-lactamase (MBL) fold (MBLf) was first observed in bacterial enzymes that catalyze the hydrolysis of almost all β-lactam antibiotics, but is now known to be widely distributed. The MBL core protein fold is present in human enzymes with diverse biological roles, including cell detox...

Popoln opis

Bibliografske podrobnosti
Main Authors: Pettinati, I, Brem, J, Lee, S, McHugh, P, Schofield, C
Format: Journal article
Jezik:English
Izdano: Elsevier 2016