The structure of 4-way DNA junctions: specific binding of bis-intercalators with rigid linkers.

During replication and recombination, two DNA duplexes lie side by side. We have developed reagents that might be used to probe structure during these critical processes; they contain two intercalating groups connected by a rigid linker that forces those groups to point in opposite directions. If th...

Full description

Bibliographic Details
Main Authors: Carpenter, M, Lowe, G, Cook, P
Format: Journal article
Language:English
Published: 1996