Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy.
Growth of the post-natal mammalian heart occurs primarily by cardiac myocyte hypertrophy. Previously, we and others have shown that a partial re-activation of the cell cycle machinery occurs in myocytes undergoing hypertrophy such that cells progress through the G1/S transition. In this study, we ha...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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