Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy.

Growth of the post-natal mammalian heart occurs primarily by cardiac myocyte hypertrophy. Previously, we and others have shown that a partial re-activation of the cell cycle machinery occurs in myocytes undergoing hypertrophy such that cells progress through the G1/S transition. In this study, we ha...

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Bibliographic Details
Main Authors: Vara, D, Bicknell, K, Coxon, C, Brooks, G
Format: Journal article
Language:English
Published: 2003