Rapid oxygen-dependent changes in erythropoietin mRNA in perfused rat kidneys: evidence against mediation by cAMP.

Erythropoietin (EPO) is mainly produced in the kidneys and is regulated by blood oxygen availability. Studies with isolated perfused kidneys have established that an oxygen-sensing system exists intrarenally but the mechanisms involved are poorly understood. Using a quantitative RNase protection ass...

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Những tác giả chính: Tan, C, Ratcliffe, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1992