Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.

We conducted a genome-wide association study to search for risk alleles associated with Tetralogy of Fallot (TOF), using a northern European discovery set of 835 cases and 5159 controls. A region on chromosome 12q24 was associated (P = 1.4 × 10(-7)) and replicated convincingly (P = 3.9 × 10(-5)) in...

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Bibliographic Details
Main Authors: Cordell, H, Töpf, A, Mamasoula, C, Postma, A, Bentham, J, Zelenika, D, Heath, S, Blue, G, Cosgrove, C, Granados Riveron, J, Darlay, R, Soemedi, R, Wilson, I, Ayers, K, Rahman, T, Hall, D, Mulder, B, Zwinderman, A, van Engelen, K, Brook, J, Setchfield, K, Bu'Lock, F, Thornborough, C, O'Sullivan, J, Stuart, A
Format: Journal article
Language:English
Published: 2013