Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials

<p>Methaemoglobin results from the oxidation of ferrous to ferric iron in the centre of the haem moiety of haemoglobin. The production of dose-dependent methaemoglobinaemia by 8-aminoquinoline antimalarial drugs appears to be associated with, but is not directly linked to, therapeutic efficacy...

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Bibliographic Details
Main Authors: White, NJ, Watson, JA, Baird, JK
Format: Journal article
Language:English
Published: Wiley 2022