Viral vectored hepatitis C virus vaccines generate pan-genotypic T cell responses to conserved subdominant epitopes
<br><strong>Background: </strong>Viral genetic variability presents a major challenge to the development of a prophylactic hepatitis C virus (HCV) vaccine. A promising HCV vaccine using chimpanzee adenoviral vectors (ChAd) encoding a genotype (gt) 1b non-structural protein (ChAd-Gt...
Autori principali: | , , , , , , , |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Elsevier
2020
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