Viral vectored hepatitis C virus vaccines generate pan-genotypic T cell responses to conserved subdominant epitopes

Viral vectored hepatitis C virus vaccines generate pan-genotypic T cell responses to conserved subdominant epitopes

<br><strong>Background: </strong>Viral genetic variability presents a major challenge to the development of a prophylactic hepatitis C virus (HCV) vaccine. A promising HCV vaccine using chimpanzee adenoviral vectors (ChAd) encoding a genotype (gt) 1b non-structural protein (ChAd-Gt...

Podrobná bibliografie
Hlavní autoři:	Donnison, T, von Delft, A, Brown, A, Swadling, L, Hutchings, C, Hanke, T, Chinnakannan, S, Barnes, E
Médium:	Journal article
Jazyk:	English
Vydáno:	Elsevier 2020

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