Antibodies expose multiple weaknesses in the glycan shield of HIV.

A shield of glycans coat the viral envelope proteins of the human immunodeficiency virus (HIV). Broadly neutralising antibodies can recognise this shield despite structural variation in these ‘self’ carbohydrate structures.

Бібліографічні деталі
Автори: Crispin, M, Bowden, T
Формат: Journal article
Мова:English
Опубліковано: Nature Publishing Group 2013
Опис
Резюме:A shield of glycans coat the viral envelope proteins of the human immunodeficiency virus (HIV). Broadly neutralising antibodies can recognise this shield despite structural variation in these ‘self’ carbohydrate structures.