Expression of glucocorticoid receptor gene isoforms in corticotropin-secreting tumors.

The molecular basis of Cushing's disease is not known. One of the most characteristic features of such tumors is their resistance to corticosteroid feedback at the pituitary level. We have hypothesized that abnormalities of the glucocorticoid receptor (GR) gene might play a role in the developm...

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Bibliographic Details
Main Authors: Dahia, P, Honegger, J, Reincke, M, Jacobs, R, Mirtella, A, Fahlbusch, R, Besser, G, Chew, S, Grossman, AB
Format: Journal article
Language:English
Published: 1997