A defect in the presentation of intracellular viral antigens is restored by interferon-gamma in cell lines with impaired major histocompatibility complex class I assembly.
Surface expression of the majority of class I major histocompatibility complex (MHC) heavy chains is known to require assembly with beta 2 microglobulin (beta 2m). To define other factors involved in class I MHC assembly, we have studied two tumor cell lines that are deficient in cell surface class...
Päätekijät: | Sibille, C, Gould, K, Hämmerling, G, Townsend, A |
---|---|
Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
1992
|
Samankaltaisia teoksia
-
Presentation of viral antigen controlled by a gene in the major histocompatibility complex.
Tekijä: Cerundolo, V, et al.
Julkaistu: (1990) -
Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum.
Tekijä: Elliott, T, et al.
Julkaistu: (1995) -
The folding, assembly, and intracellular transport of murine class I major histocompatibility complex heavy chains
Tekijä: Machold, Robert Pulleyn
Julkaistu: (2008) -
Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules
Tekijä: Roberto Rosales-Reyes, et al.
Julkaistu: (2020-01-01) -
Defective assembly of class I major histocompatibility complex molecules in an embryonic cell line.
Tekijä: Bikoff, E, et al.
Julkaistu: (1991)