Use of deterministic sampling for exploring likelihoods in linkage analysis for quantitative traits.

Deterministic sampling was used to numerically evaluate the expected log-likelihood surfaces of QTL-marker linkage models in large pedigrees with simple structures. By calculating the expected values of likelihoods, questions of power of experimental designs, bias in parameter estimates, approximate...

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Bibliographic Details
Main Authors: Mackinnon, M, van der Beek, S, Kinghorn, B
Format: Journal article
Language:English
Published: 1996