Use of deterministic sampling for exploring likelihoods in linkage analysis for quantitative traits.
Deterministic sampling was used to numerically evaluate the expected log-likelihood surfaces of QTL-marker linkage models in large pedigrees with simple structures. By calculating the expected values of likelihoods, questions of power of experimental designs, bias in parameter estimates, approximate...
Main Authors: | Mackinnon, M, van der Beek, S, Kinghorn, B |
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Format: | Journal article |
Language: | English |
Published: |
1996
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