Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.

BACKGROUND: Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analy...

Full description

Bibliographic Details
Main Authors: Lim, C, Wannapinij, P, White, L, Day, N, Cooper, B, Peacock, S, Limmathurotsakul, D
Format: Journal article
Language:English
Published: Public Library of Science 2013