Measuring kinetic drivers of pneumolysin pore structure.

Most membrane attack complex-perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins are thought to form pores in target membranes by assembling into pre-pore oligomers before undergoing a pre-pore to pore transition. Assembly during pore formation is into both full rings of subunits and incom...

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Bibliographic Details
Main Authors: Gilbert, R, Sonnen, A
Format: Journal article
Language:English
Published: Springer 2016