Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.
A neuronal isoform of nitric oxide synthase (nNOS) has recently been located to the cardiac sarcoplasmic reticulum (SR). Subcellular localization of a constitutive NOS in the proximity of an activating source of Ca2+ suggests that cardiac nNOS-derived NO may regulate contraction by exerting a highly...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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