Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.
A neuronal isoform of nitric oxide synthase (nNOS) has recently been located to the cardiac sarcoplasmic reticulum (SR). Subcellular localization of a constitutive NOS in the proximity of an activating source of Ca2+ suggests that cardiac nNOS-derived NO may regulate contraction by exerting a highly...
Main Authors: | Sears, C, Bryant, S, Ashley, E, Lygate, C, Rakovic, S, Wallis, H, Neubauer, S, Terrar, D, Casadei, B |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
2003
|
Lignende værker
-
A cardiac neuronal nitric oxide synthase isoform regulates contraction and calcium handling in murine ventricular myocytes
af: Sears, C, et al.
Udgivet: (2002) -
A cardiac neuronal nitric oxide synthase isoform regulates contraction and calcium handling in murine ventricular myocytes
af: Sears, C, et al.
Udgivet: (2002) -
A cardiac nitric oxide synthase 1 regulates contraction and calcium fluxes - a novel mechanism in the autocrine control of cardiac function
af: Ashley, E, et al.
Udgivet: (2002) -
Neuronal nitric oxide synthase (NOS1) regulates beta-adrenergic contraction and calcium handling in isolated murine ventricular myocytes
af: Zhang, Y, et al.
Udgivet: (2003) -
Nitric oxide synthase 1 (NOS1) regulates basal and beta-adrenergic left-ventricular contraction and relaxation in vivo
af: Ashley, E, et al.
Udgivet: (2003)