Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.

Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.

A neuronal isoform of nitric oxide synthase (nNOS) has recently been located to the cardiac sarcoplasmic reticulum (SR). Subcellular localization of a constitutive NOS in the proximity of an activating source of Ca2+ suggests that cardiac nNOS-derived NO may regulate contraction by exerting a highly...

Полное описание

Библиографические подробности
Главные авторы:	Sears, C, Bryant, S, Ashley, E, Lygate, C, Rakovic, S, Wallis, H, Neubauer, S, Terrar, D, Casadei, B
Формат:	Journal article
Язык:	English
Опубликовано:	2003

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