Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.

A number of acute leukemias arise from fusion of the mixed lineage leukemia 1 protein (MLL) N terminus to a variety of fusion partners that have been reported to reside in one or more poorly defined complexes linked to transcription elongation through interactions with the histone H3-K79 methyltrans...

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Bibliographic Details
Main Authors: Biswas, D, Milne, T, Basrur, V, Kim, J, Elenitoba-Johnson, K, Allis, C, Roeder, R
Format: Journal article
Language:English
Published: 2011