Suppression of virus specific immune responses by IL-10 in acute dengue infection

BACKGROUND: Elevated IL-10 has been shown to be associated with severe dengue infection (DI). We proceeded to investigate the role of IL-10 in the pathogenesis of acute DI. MATERIALS AND METHODS: Ex vivo and cultured IFNγ ELISpot assays for dengue virus (DENV) NS3 protein and non dengue viral protei...

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Hlavní autoři: Malavige, G, Jeewandara, C, Alles, K, Salimi, M, Gomes, L, Kamaladasa, A, Jayaratne, S, Ogg, G
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2013