Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

Hypoxia‐inducible factor (HIF) directs an extensive transcriptional cascade that transduces numerous adaptive responses to hypoxia. Pan‐genomic analyses, using chromatin immunoprecipitation and transcript profiling, have revealed large numbers of HIF‐binding sites that are generally associated with...

Description complète

Détails bibliographiques
Auteurs principaux: Platt, J, Salama, R, Smythies, J, Choudhry, H, Davies, J, Hughes, J, Ratcliffe, P, Mole, D
Format: Journal article
Langue:English
Publié: EMBO Press 2016