Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.
Hypoxia is an important regulator of normal and cancer stem cell (CSC) differentiation. Colorectal CSCs from SW1222, LS180, and CCK81 colorectal cancer-derived cell lines are able to differentiate into complex 3D lumen-containing structures in normoxia, whereas in hypoxia, they form undifferentiated...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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