Th1 and Th2 cells form morphologically distinct immunological synapses.

The arrangement of molecules at the interface between T cells and APCs is known as the immunological synapse (IS). We conducted experiments with supported planar bilayers and transfected fibroblast APC to examine the IS formed by polarized Th1 and Th2 cells. Th1 cells formed typical "bull'...

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Bibliographic Details
Main Authors: Thauland, T, Koguchi, Y, Wetzel, SA, Dustin, M, Parker, D
Format: Journal article
Language:English
Published: 2008