Structure-based optimization of coumarin hA3 adenosine receptor antagonists

Adenosine receptors are involved in several physiological processes. Molecules able to selectively modulate one of these receptors represent promising multifunctional agents to treat or slow down the progression of different diseases. 3-Arylcoumarins have already been studied as neuroprotective agen...

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Bibliographic Details
Main Authors: Matos, M, Vilar, S, Vazquez-Rodriguez, S, Kachler, S, Klotz, K, Buccioni, M, Delogu, G, Santana, L, Uriarte, E, Borges, F
Format: Journal article
Language:English
Published: American Chemical Society 2019