EXD2 promotes homologous recombination by facilitating DNA end resection

Repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is critical for survival and genome stability of individual cells and organisms, but also contributes to the genetic diversity of species. A vital step in HR is MRN-CtIP-dependent end resection, which generates the 3' si...

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Detaylı Bibliyografya
Asıl Yazarlar: Niedzwiedz, W, Broderick, R, Nieminuszczy, J, Baddock, H, Deshpande, R, Paull, T, Gileadi, O, McHugh, P
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Nature Publishing Group 2016