Conditional disorder in small heat-shock proteins

Small heat-shock proteins (sHSPs) are molecular chaperones that respond to cellular stresses to combat protein aggregation. HSP27 is a critical human sHSP that forms large, dynamic oligomers whose quaternary structures and chaperone activities depend on environmental factors. Upon exposure to cellul...

Full description

Bibliographic Details
Main Authors: Alderson, TR, Ying, J, Bax, A, Benesch, JLP, Baldwin, AJ
Format: Journal article
Language:English
Published: Elsevier 2020