Histone deacetylase inhibitors enhance CD4 T cell susceptibility to NK cell killing but reduce NK cell function
In the search for a cure for HIV-1 infection, histone deacetylase inhibitors (HDACi) are being investigated as activators of latently infected CD4 T cells to promote their targeting by cytotoxic T-lymphocytes (CTL). However, HDACi may also inhibit CTL function, suggesting different immunotherapy app...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Public Library of Science
2016
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