Role of HLA class II and cytokine expression in rheumatoid arthritis.

HLA class II expression is notable in rheumatoid arthritis. We have investigated the mechanism of HLA class II regulation in the joints and found local synthesis, as judged by mRNA levels to be high. The role of antigen presentation in maintaining class II mRNA was explored, and blocking presentatio...

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Bibliographic Details
Main Authors: Feldmann, M, Kissonerghis, A, Buchan, G, Brennan, F, Turner, M, Haworth, C, Barrett, K, Chantry, D, Ziegler, A, Maini, R
Format: Journal article
Language:English
Published: Informa Healthcare 1988