Role of HLA class II and cytokine expression in rheumatoid arthritis.

HLA class II expression is notable in rheumatoid arthritis. We have investigated the mechanism of HLA class II regulation in the joints and found local synthesis, as judged by mRNA levels to be high. The role of antigen presentation in maintaining class II mRNA was explored, and blocking presentatio...

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Hlavní autoři: Feldmann, M, Kissonerghis, A, Buchan, G, Brennan, F, Turner, M, Haworth, C, Barrett, K, Chantry, D, Ziegler, A, Maini, R
Médium: Journal article
Jazyk:English
Vydáno: Informa Healthcare 1988