Role of HLA class II and cytokine expression in rheumatoid arthritis.

HLA class II expression is notable in rheumatoid arthritis. We have investigated the mechanism of HLA class II regulation in the joints and found local synthesis, as judged by mRNA levels to be high. The role of antigen presentation in maintaining class II mRNA was explored, and blocking presentatio...

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Dades bibliogràfiques
Autors principals: Feldmann, M, Kissonerghis, A, Buchan, G, Brennan, F, Turner, M, Haworth, C, Barrett, K, Chantry, D, Ziegler, A, Maini, R
Format: Journal article
Idioma:English
Publicat: Informa Healthcare 1988