Of mice and men: cytotoxic T cells and AIDS pathogenesis.

CD8+ cytotoxic T lymphocytes (CTLs) represent a first line of defense against HIV infection, although their precise role in disease pathogenesis remains enigmatic. They play an important part in viral control but may also contribute to disease progression through destruction of CD4+ helper T cells....

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Bibliographic Details
Main Authors: Klenerman, P, Zinkernagel, R
Format: Journal article
Language:English
Published: 1999