A formal synthesis of (-)-pumiliotoxin C
An asymmetric synthesis of an advanced intermediate in the synthesis of natural (-)-pumiliotoxin C has been achieved in six steps and in 61% overall yield employing as the key step a highly diastereoselective lithium amide 1,4-conjugate addition to a dienoic ester derived from (R)-(+)-pulegone.
| Main Authors: | , |
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| Format: | Journal article |
| Published: |
1996
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