A formal synthesis of (-)-pumiliotoxin C
An asymmetric synthesis of an advanced intermediate in the synthesis of natural (-)-pumiliotoxin C has been achieved in six steps and in 61% overall yield employing as the key step a highly diastereoselective lithium amide 1,4-conjugate addition to a dienoic ester derived from (R)-(+)-pulegone.
| Những tác giả chính: | , |
|---|---|
| Định dạng: | Journal article |
| Được phát hành: |
1996
|