Structural investigations of the inhibition of escherichia coli AmpC β-lactamase by diazabicyclooctanes
β-Lactam antibiotics are presently the most important treatments for infections by pathogenic Escherichia coli, but their use is increasingly compromised by β lactamases, including the chromosomally encoded class C AmpC serine-β lactamases (SBL). The diazabicyclooctane (DBO) avibactam is a potent Am...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Society for Microbiology
2021
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