Antibody repertoire analysis in polygenic autoimmune diseases

High-throughput sequencing of the DNA/RNA encoding antibody heavy- and light-chains is rapidly transforming the field of adaptive immunity. It can address key questions, including: (i) how the B-cell repertoire differs in health and disease; and (ii) if it does differ, the point(s) in B-cell develop...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Bashford-Rogers, R, Smith, K, Thomas, D
Format: Journal article
Sprog:English
Udgivet: Wiley 2018